Certified Registered Nurse Infusion (CRNI) Practice Exam

Exceeding the osmolarity limit for intravenous solutions can lead to phlebitis, which is characterized by inflammation of the vein. When an infusion solution has a higher osmolarity than the blood, it can cause irritation to the endothelial lining of the blood vessel. This irritation triggers an inflammatory response, resulting in symptoms such as redness, swelling, pain, and warmth at the infusion site. Over time, if this condition is not managed properly, it can lead to further complications, including thrombosis or local infection.

The role of osmolarity in intravenous therapy is crucial, as solutions that are too concentrated can draw fluid from the surrounding tissues into the vein, leading to cellular dehydration and inflammation. Proper management of osmolarity is essential to prevent complications like phlebitis, ensuring a safe and effective infusion therapy experience for the patient.