Certified Registered Nurse Infusion (CRNI) Practice Exam

Amphotericin B is an antifungal medication widely used to treat serious fungal infections. A common adverse effect associated with this medication is flu-like symptoms, which can manifest as fever, chills, malaise, and muscle aches. These symptoms often occur shortly after administration and are thought to be a result of the drug's effects on the immune system as it combats fungal pathogens.

The reaction is generally expected and can usually be managed with premedication using antipyretics or corticosteroids to help alleviate these symptoms. Understanding that flu-like symptoms are frequently encountered can help healthcare providers prepare and educate patients regarding possible reactions, thus promoting better patient compliance and comfort during treatment.

While acute renal failure is also a notable adverse effect of Amphotericin B and can be severe, it is less common than the flu-like symptoms experienced early in treatment. The other options, including severe hypotension and visual disturbances, are not typically associated with Amphotericin B in the same frequent manner as flu-like symptoms.